|
|
Bylinné čaje a jejich antioxidanty
Ilčíková, Ladislava
In its first part, this Bachelor thesis named Herbal Teas and Their Antioxidants defines the term free radical and oxidative stress. Firstly, it discusses antioxidants which are presented in vegetal materials. It divides them into categories pursuant to their origin and their structure, and to other significant antioxidants and it researches their medicinal properties in relation to various groups of diseases, Secondly, it explains the consequences of excessive intake of antioxidants. The second part of this work deals with the preparation of herbal teas and their proper use. t characterizes twenty widely known and lesser-known herbs, which are most often being used to prepare herbal tea and it talks about their effect on human health. Free radicalm oxidative stress, antioxidants, herbal teas, vegetla antioxidants, herbs
|
|
|
Natural compounds in foods with anti-cancer effects
Soukup, Josef ; Orsák, Matyáš (advisor) ; Hnilička, František (referee)
In this thesis, I focus on natural substances which are present in commonly available foods and their effects can not only considerably prevent, but also help treat cancer. As this is a very extensive topic, included are only substances which have been studied for this purpose for a long time and which have a large potential in this area. These are phenolic compounds, carotenoids, sulfur compounds, substances found in cruciferous vegetables or green tea, beta-glucans and their sources, and other health beneficial foods such as turmeric, ginger or garlic. I also mention several vitamins (C, E, A, D) which directly show anti-cancer effects or are used in combination with other means to increase the efficiency of the treatment. The deficiency of some other essential vitamins and minerals increase the risk of certain types of cancer as well and a large amount of anti-cancer acting compounds can be also found in herbs, exotic mushrooms, marine organisms and microorganisms, but that area exceeds the content of this thesis. Although nowdays there are substances targeted at only one symptom and can have a certain effect, these medicaments are associated with many side effects and are also expensive. The contemporary paradigm for cancer treatment is either combine several single-targeted medicaments or come up with medicaments that modulate multiple targets. Various types of cancer have similar character, but due to a different etiology of each type and different effect of individual anti-cancer substances (even belonging in the same chemical group), the efficiancy of these compounds against various types of cancer, mostly depending on metabolism, distribution in organism and the target use, differs significantly. Therefore, some substances can show a very strong anti-cancer effect at certain cancer types, while almost none at different types. Other factors such as biological availability or stability make utilization of many compounds more difficult. Basic types of anti-cancer effects are: antioxidant effects (the ability to scavenge free radicals), antiproliferative effects (the inhibition of uncontrolled growth), the ability to induce apoptosis (induction of programmed cell death), the ability to inhibit metastasis and anti-angiogenic effects (prevention of the formation of new blood vessels of the tumor).
|
guest ::
